Table 3.
Association between non-adherence to mCOPD medications and non-adherence to non-COPD medications: logistic regression analysisa
| Variable | Odds ratio | Lower 95% CI | Upper 95% CI | P-value |
|---|---|---|---|---|
| Dependent variable | ||||
| Non-adherence (PDC <0.8) to mCOPD medications | NA | NA | NA | NA |
| Main independent variables | ||||
| Non-adherence (PDC <0.8) to | ||||
| Statins | 1.54 | 1.37 | 1.74 | <0.0001 |
| Antihypertensives | 1.55 | 1.38 | 1.74 | <0.0001 |
| Anticoagulants | 1.21 | 0.93 | 1.57 | 0.1497 |
| Oral antihyperglycemics | 1.38 | 1.13 | 1.69 | 0.0019 |
| Insulins | 1.78 | 1.28 | 2.47 | 0.0005 |
| Antidepressants | 1.73 | 1.50 | 1.99 | <0.0001 |
| NSAIDs | 1.74 | 1.39 | 2.18 | <0.0001 |
| Antianxiety | 1.16 | 0.93 | 1.45 | 0.1873 |
| Calcium channel blockers | 1.53 | 1.31 | 1.78 | <0.0001 |
| Beta-blockers | 1.39 | 1.21 | 1.61 | <0.0001 |
| Bisphosphonates | 1.51 | 1.20 | 1.91 | 0.0005 |
| Diuretics | 1.44 | 1.27 | 1.63 | <0.0001 |
Notes:
a
Study population, n=14,117. Baseline patient characteristics including age, sex, region, influenza vaccination status, and RxRisk-V score were included in the model as covariates.
Abbreviations: CI, confidence interval; mCOPD, maintenance COPD; NA, not applicable; NSAIDs, nonsteroidal anti-inflammatory drugs; PDC, proportion of days covered.