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. Author manuscript; available in PMC: 2018 Jan 5.
Published in final edited form as: Vaccine. 2016 Dec 3;35(2):329–336. doi: 10.1016/j.vaccine.2016.11.059

Figure 3. Plasmablast frequency increases proportionally to the increase in frequency of ICOS+ pTfh cells after vaccination.

Figure 3

A) Plasmablasts, defined as CD19+ CD20lowCD38highCD27high. cells were measured before and after vaccination. B) The frequency of plasmablasts before and after vaccination for each individual. C) The change in plasmablast frequency from day 0 to day 7 correlated directly with the change in ICOS+ pTfh cells. Spearman’s rank correlation was performed on the whole cohort Subjects who received standard dose or high dose are indicated. D) Plasmablast frequency for either the SD IIV or the HD IIV group before and after vaccination.

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