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. Author manuscript; available in PMC: 2018 Jan 5.
Published in final edited form as: Vaccine. 2016 Dec 3;35(2):329–336. doi: 10.1016/j.vaccine.2016.11.059

Figure 4. The change in frequency of ICOS+ pTfh cells day 7 after vaccination correlated with day 28 HAI titers and predicted seroconversion.

Figure 4

A) The change in ICOS+ pTfh cells directly correlated with the day 28 HAI titer for both strains of influenza A but not influenza B (Spearman’s rank). B) The change in ICOS+ pTfh cells was significantly greater in seroconverters compared to non-converters (Mann-Whitney U test). Open triangles indicate standard dose recipients; closed circles are high dose recipients.

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