Table 1.
50 adults at least 65 years old were randomized to receive either high dose or standard dose IIV. Comparison of age was calculated with an unpaired t-test. Comparisons between doses for seroprotection at day 28 and seroconversion were calculated with Fisher’s exact test.
Standard dose n=24 | High dose n =26 | p | |
---|---|---|---|
Age mean (IQR) | 73 (68, 77) | 72 (65, 77) | 0.45 |
H1N1 | |||
Seroprotection | 54% | 81% | 0.03 |
Seroconversion | 33% | 54% | 0.16 |
H3N2 | |||
Seroprotection | 46% | 87% | 0.002 |
Seroconversion | 25% | 81% | <0.001 |
B | |||
Seroprotection | 58% | 81% | 0.12 |
Seroconversion | 4% | 46% | <0.001 |