Table 1.
SLE Cases N=149 |
Controls N=126 |
p value | |
---|---|---|---|
Traditional CVD Risk Factors | |||
Age (years), mean (SD) | 48.6 (10.1) | 52.2 (10.1) | 0.003 |
African American, n (%) | 42 (28.2%) | 27 (21.4%) | 0.290 |
Body Mass Index (kg/m2), mean (SD) | 28.4 (8.1) | 29.8 (10.9) | 0.260 |
Current Smoker, n (%) | 10 (6.8%) | 8 (6.4%) | 0.890 |
Systolic Blood Pressure (mmHg), mean (SD) | 114.0 (15.1) | 118.9 (15.7) | 0.010 |
Hypertension, n (%) | 86 (58.7%) | 40 (31.8%) | <.0001 |
Diabetes, n (%) | 10 (6.7%) | 1 (0.79%) | 0.013 |
Total cholesterol: HDL ratio, mean (SD) | 3.69 (1.42) | 3.54 (1.05) | |
Statin use, n (%) | 29 (19.5%) | 17 (13.5%) | 0.186 |
Aspirin use, n (%) | 37 (24.8%) | 19 (15.1%) | 0.045 |
Prednisone use, n (%) | 56 (37.6%) | N/A | N/A |
Prednisone dose (mg), mean (SD)* | 12.06 (8.66) | N/A | N/A |
Serum creatinine (mg/dL), mean (SD) | 0.93 (1.16) | 0.75 (0.13) | 0.053 |
SLE-Related Factors | |||
SLICC/ACR-DI, mean (SD) | 2.7 (3.3) | N/A | N/A |
SLEDAI-2K, mean (SD) | 2.3 (2.3) | N/A | N/A |
Depression-related factors | |||
CES-D ≥ 16, n (%) | 43 (28.9%) | 14 (11.1%) | <0.001 |
Of 56 patients taking prednisone at baseline visit