Table 2.
SLE Cases Not Depressed N=106 |
SLE Cases Depressed N=43 |
p value | |
---|---|---|---|
Traditional CVD Risk Factors | |||
Age (years), mean (SD) | 48.28 (10.86) | 49.36 (7.96) | 0.504 |
African American, n (%) | 26 (24.53%) | 16 (37.21%) | 0.189 |
Body Mass Index (kg/m2), mean (SD) | 27.38 (7.47) | 30.98 (9.09) | 0.014 |
Current Smoker, n (%) | 6 (5.71%) | 4 (9.30%) | 0.477 |
Systolic Blood Pressure (mmHg), mean (SD) | 113.08 (14.60) | 116.30 (16.13) |
0.239 |
Diabetes, n (%) | 6 (5.66%) | 4 (9.30%) | 0.475 |
Total cholesterol: HDL ratio, mean (SD) | 3.60 (145) | 3.90 (1.33) | 0.250 |
Serum creatinine, mean (SD) | 0.98 (1.36) | 0.83 (0.22) | 0.296 |
Statin use, n (%) | 22 (20.75%) | 7 (16.28%) | 0.532 |
Aspirin use, n (%) | 22 (20.75%) | 15 (34.88%) | 0.071 |
Prednisone use, n (%) | 33 (31.1%) | 23 (53.5%) | 0.011 |
Prednisone dose, mean (SD)* | 13.4 (9.83) | 10.1 (6.34) | 0.135 |
SLE-Related Factors | |||
SLICC/ACR-DI, mean (SD) | 2.62 (2.83) | 2.95 (1.81) | 0.640 |
SLEDAI-2K, mean (SD) | 2.21 (2.41) | 2.60 (1.81) | 0.293 |
Depression-related factors | |||
CES-D , mean (SD) | 5.75 (4.59) | 25.70 (8.25) | <.0001 |
Of 23 depressed and 33 not depressed patients taking prednisone at baseline visit