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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Alcohol. 2016 Jun 27;58:33–45. doi: 10.1016/j.alcohol.2016.05.007

Table 1.

Genes for potassium channels in the nucleus accumbens that significantly correlated with voluntary consumption in non-dependent BXD strains of mice (n = 24 strains).

Gene Probe set Protein r R2 P value Functional Class Subcellular Localization
Kcna1 1455785_at KV1.1 0.514 0.264 0.009 Delayed rectifier voltage-gated Axon/Terminals
Kcnab3 1436019_a_at KVβ3 0.461 0.213 0.022 β subunit, KV1.5 modifier Axon/Terminals
Kcnb1 1440838_at KV2.1 −0.404 0.163 0.050 Delayed rectifier voltage-gated Somatodendritic
Kcnd2 1433015_at KV4.2 −0.684 0.468 1.25−04 A-type voltage-gated Dendrites
1446065_at −0.665 0.442 2.42−04
1458167_at −0.599 0.359 0.002
1459288_at −0.580 0.337 0.002
Kcne1l 1416640_at minK −0.610 0.372 0.001 β subunit modulator of KV7.1 and KV12.2 Axon/Terminals
Kcnj15 1435354_at Kir4.2 0.417 0.174 0.042 Inwardly rectifying Unknown
Kcnj3 1444025_at Kir3.1 0.438 0.192 0.031 G protein-gated, inwardly rectifying Dendrites
1455374_at 0.430 0.185 0.035
Kcnk4 1421419_at K2P4.1 0.453 0.205 0.025 Two-pore domain open rectifier Intracellular
Kcnma1 1440728_at KCa1.1 −0.502 0.252 0.011 Large conductance, calcium- and voltage-activated Axon/Terminals
1444973_at −0.466 0.217 0.021
1457018_at −0.426 0.182 0.037
1445774_at −0.415 0.173 0.043
1430276_at 0.522 0.272 0.008
Kcnn1 1419617_at KCa2.1 0.469 0.220 0.020 Small-conductance, calcium-activated Dendrites
Kcnn3 1459308_at KCa2.3 −0.551 0.304 0.005 Small-conductance, calcium-activated Dendrites
Kcnq1 1458161_at KV7.1 −0.734 0.538 1.78−05 M-current delayed rectifier Axon/Terminals
1457781_at −0.644 0.415 4.52−04
1441588_at −0.545 0.297 0.005
1442029_at −0.476 0.226 0.018
1446255_at −0.406 0.165 0.048
Kcnq2 1440258_at KV7.2 −0.573 0.328 0.003 M-current delayed rectifier Axon/Terminals
1451595_a_at −0.537 0.289 0.006
1438260_at −0.515 0.265 0.009
Kcnq5 1446537_at KV7.5 −0.581 0.338 0.002 M-current delayed rectifier Axon/Terminals
1445837_at −0.572 0.328 0.003
1457898_at −0.561 0.315 0.004
1433110_at −0.523 0.274 0.008
Kcnt1 1458428_at KCa4.1 −0.477 0.227 0.017 Sodium-activated, voltage-gated Somatodendritic
1439486_at −0.470 0.220 0.020
Kcnv1 1453273_at KV8.1 0.446 0.199 0.028 Modifier/silencer of KV2 currents Unknown
1439333_at 0.421 0.177 0.040