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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Neuroimage. 2016 Jun 27;139:405–414. doi: 10.1016/j.neuroimage.2016.06.044

Fig. 2.

Fig. 2

a) Simulated time-activities of a reference region (gray) and target region (black) for relatively low-binding regions using (a) BP = 1 and 1/k4 = 15 min. b) The corresponding ratio of bound to total concentration of PET ligand in the target region versus time (black points) is compared to the model estimate for SRTM (red) and FRTM using values of 1/k4 from 5 to 25 minutes.