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. Author manuscript; available in PMC: 2018 Jan 5.
Published in final edited form as: Vaccine. 2016 Nov 29;35(2):264–272. doi: 10.1016/j.vaccine.2016.11.072

Fig. 7. Membrane Feeding Assays.

Fig. 7

Transmission blocking activity of purified IgG from pooled immune sera from mice immunized with SYN Pfs25 and SYN Pfs48/45 DNA vaccines, individually or with a combination (with EP) was determined using MFA. Scatter plots represent the number of oocysts counted in individual mosquitoes and the median oocyst counts by the horizontal bars. Geometric mean oocyst counts were used to calculate percent transmission reducing activity shown by numbers within a box above each scatter plot. Numbers within the rectangular box below show the total number of mosquitoes infected / total number of mosquitoes dissected for each group. These MFAs were done at the same time as those in Fig. 6b and SYN Pfs48/45 data is included here for comparison. Statistical significance was analyzed by Mann Whitney U test and are indicated by an asterisk (*).