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In vivo Binding potential definitions
| Outcome measure: | In vitro equation | What specific tracer binding is compared to: |
Units | Requirement of blood sampling |
|---|---|---|---|---|
| BPF | =Bavail/KD | Free plasma concentration | mL cm−3 | Yes |
| BPND | =fND*Bavail/KD | Nondisplacable uptake | Unitless | No |
Bavail is the concentration of unoccupied receptors, KD is the tracer dissociation constant, fp is the free fraction of tracer in the nondisplacable compartment. This table is adapted from Innis et al. (2007).
