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. 2016 Dec 27;4:16037. doi: 10.1038/boneres.2016.37

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Copyright © 2016 The Author(s)

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Chromatin Immunoprecipitation (ChIP) assays of OVX and Sham mouse BMMSCs. (a) Dimethylation level of histone H3 at lysine 4 (H3K4) at the promoter region of Runx2 of Sham BMMSCs at 7 days after adding pargyline. (b) Dimethylation level of H3K4 at the promoter region of Runx2 of OVX BMMSCs at 7 days after adding pargyline. (c) Dimethylation level of H3K4 at the promoter region of OC of Sham BMMSCs at 7 days after adding pargyline. (d) Dimethylation level of H3K4 at the promoter region of OC of OVX BMMSCs at 7 days after adding pargyline. *P<0.05. n=6. OM, osteogenic medium; OP, OM with 1.5 mmol·L⁻¹ pargyline; PM, proliferation medium; PP, PM with 1.5 mmol·L⁻¹ pargyline.