Skip to main content
. 2016 Dec 16;5(12):e117. doi: 10.1038/cti.2016.72

Figure 8.

Figure 8

Enhancing activity of anti-DENV human sera against ZIKV PRVABC59 by infectious particle and qRT–PCR assays. The effect of anti-DENV human sera on the production of (a) replication of viral RNA and on (b) infectious progeny viral particles was determined in the human FcRII bearing cell line K562 infected with ZIKV PRVABC59 in the presence (1:50 000 dilution) or absence (0=no serum control) of Singapore 1 serum. The presence of enhancing serum resulted in a large and statistically significant increase in the amount of viral RNA (T-test, P=0.000015) as well as infectious progeny virus released (T-test, P=0.00077).