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. 2016 Dec 9;48(12):e277. doi: 10.1038/emm.2016.129

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Copyright © 2016 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/

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The expression of energy metabolism-related genes is negatively correlated with the prognosis of lung adenocarcinoma. (a) Correlations between the expression of energy metabolism-related genes and prognosis were analyzed using an open database²⁰ with the data of 866 lung adenocarcinoma patients. The percentage of genes associated with a particular prognosis in each metabolic pathway subset is shown. Blue, positive prognosis; red, negative prognosis; gray, no difference in prognosis or unclear. (b) Mitochondrial complex 1 genes and their associations with overall survival. A list of all genes in specific metabolic pathways and their correlations with prognosis is shown in Supplementary Table 1. (c) Schematic diagram of the associations of mitochondrial oxidative phosphorylation (OxPhos) complex genes with MMP.