TABLE 2.
Study | Target Spo2 Arm | Median Spo2, % | Tail, Proportion of Time Spent at This Spo2 Level, % | Original, % | Revised, % | |
---|---|---|---|---|---|---|
Original | Revised | |||||
COTa | 85%–89% (low) | 91 | 91 | <85 | 20.2 | 18.5 |
>95 | 17.5 | 15.2 | ||||
91%–95% (high) | 93 | 93 | <85 | 9.1 | 8.2 | |
>95 | 22.4 | 21.2 | ||||
BOOST-II UKb | 85%–89% (low) | 91 | 90 | <85 | 25.7 | 22.1 |
>95 | 16.1 | 13.9 | ||||
91%–95% (high) | 92 | 93 | <85 | 15.0 | 12.3 | |
>95 | 18.7 | 20.4 | ||||
BOOST-II Australiab | 85%–89% (low) | 90 | 89 | <85 | 27.4 | 24.1 |
>95 | 11.1 | 8.1 | ||||
91%–95% (high) | 93 | 92 | <85 | 13.5 | 10.8 | |
>95 | 18.6 | 16.4 | ||||
BOOST-II New Zealandb | 85%–89% (low) | 91 | <85 | 21.1 | Only oximeters with the original algorithm were used in these studies. | |
>95 | 15.5 | |||||
91%–95% (high) | 93 | <85 | 10.8 | |||
>95 | 22.2 | |||||
SUPPORTb | 85%–89% (low) | 90c | <85 | 10.9 | ||
>95 | 33.0 | |||||
91%–95% (high) | 93c | <85 | 16.0 | |||
>95 | 26.7 |
All study days with >12 hours of supplemental O2.
Time when the infant was receiving oxygen.
Estimate based on visual inspection of the graphs.