FIG 7.

Test of the cytotoxicity of organotellurides. Three different mammalian cell lines were used to test the cytotoxicity (see Materials and Methods for further details) of the organotellurium compounds 1 to 5; J774 (A [macrophages]), HFF (B [fibroblasts]), and HaCaT (C [keratinocytes]). Each compound was tested at three 25, 50, and 100 μM concentrations (i.e., compound 1 was tested at 8, 17, and 34 μg/ml, compound 2 at 9, 18, and 35 μg/ml, compound 3 at 9, 18, and 36 μg/ml, compound 4 at 9, 19, and 38 μg/ml, and compound 5 at 10, 20, and 40 μg/ml, respectively). The data are the means ± the standard errors from three independent experiments.