Effect of organotellurides on CaCDR1, CaCDR2, CaMDR1, and CaERG11 mRNA expression levels of C. albicans clinical FLC-resistant isolates. (A) mRNA expression levels of C. albicans 95-142 in the presence of compounds 1, 2, and 3. (B) mRNA expression levels of C. albicans 96-25. (C) mRNA expression levels of C. albicans 12-99. All mRNA levels were normalized relative to the housekeeping gene ACT1. The data represent the means ± the standard errors from three independent experiments, and each value was then compared to its ACT1 control (*, P < 0.05). The mRNA expression levels of a wild-type, FLC-sensitive C. albicans clinical isolate (2-76) are shown for comparison.