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. 2016 Dec 27;61(1):e01651-16. doi: 10.1128/AAC.01651-16

TABLE 3.

Antibiotic susceptibilities of pbp mutant strains in PA14

Strain Genotype MICa (μg/ml)
IMP DOP CEP CESD CAZ PIP PenG ATM
PA14 Wild type 1 0.25 2 4 4 4 2,048 8
CW29 ΔponATP 1 0.25 2 2 4 4 2,048 8
CW31 ΔmrcBTP 1 0.25 2 2 4 4 512 8
CW37 ΔpbpA 0.25 0.25 2 4 4 4 256 8
CW46b ΔftsI 0.25 0.125 0.25 0.5 0.5 1 64 1
CW30 ΔponATP pbpA::Gm 0.25 0.25 2 16 4 64 1,024 8
CW34 ΔmrcBTP pbpA::Gm 0.25 0.25 2 4 4 4 512 8
CW47b ΔponATP rmrcBTP 1 0.25 1 2 2 4 256 8
a

IMP, imipenem; DOP, doripenem; CEP, cefepime; CESD, cefsulodin; CAZ, ceftazidime; PIP, piperacillin; PenG, penicillin G; ATM, aztreonam.

b

Strains CW46 and CW47 were grown in LB supplemented with 0.2% glucose, which was used to repress ectopic expression of PBP3 and PBP1a, respectively.