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A. Insulin resistance pathway-based unidirectional weighted networks with 13 nodes and 78 edges for MCIs and HCs. The connectivity about the thresholds (r = 0.3) was shown. The figure was created using BrainNet Viewer (http://www.nitrc.org/projects/bnv/). B. Changed ROI-to-ROI connectivity between HCs and MCIs. *Indicates significant differences for MCI compared with HC, P < 0.05.
