Table 2.

Effect of perfusion of isolated rat hearts with oleuropein at the beginning of reperfusion on myocardial function parameters.

	Base	Ie	R5	R10	R30	R60	R90
HR
Con-T	292 ± 15	0 ± 0	252 ± 29	249 ± 21	242 ± 11	255 ± 23	246 ± 37
O10	285 ± 28	0 ± 0	219 ± 10	240 ± 18	241 ± 11	233 ± 10	239 ± 13
O50	282 ± 16	0 ± 0	232 ± 8.4	263 ± 14	227 ± 9	225 ± 12	220 ± 8
LVEDP
Con-T	5.3 ± 0.5	26 ± 4.1	58 ± 7.2	51 ± 6.2	48 ± 5.1	40 ± 3.3	37 ± 2.5
O10	4.2 ± 0.7	21 ± 6	47 ± 4.3 a	35 ± 5.6 a	30 ± 5 b	27 ± 3.2 b	25 ± 2.2
O50	4.4 ± 0.7	23 ± 3.2	42 ± 2.1	32 ± 3.5 b	24 ± 3.3 c	22 ± 3 c	21 ± 2.6 c
LVDP
Con-T	114 ± 8.7	0 ± 0	83 ± 2.7	76 ± 4	72 ± 3.5	61 ± 3.3	53 ± 3.1
O10	122 ± 5.4	0 ± 0	104 ± 6.7	95 ± 5.5 b	85 ± 5.3 a	79 ± 6.1 a	72 ± 6.1 b
O50	112 ± 5.1	0 ± 0	113 ± 3.3	102 ± 5.6 b	97 ± 6.6 b	91 ± 6.3 b	81 ± 6.4 b
max dp/dt
Con-T	4493 ± 357	0 ± 0	3065 ± 345	2639 ± 271	2289 ± 268	2139 ± 185	2182 ± 256
O10	5260 ± 292	0 ± 0	4111 ± 357 a	3857 ± 428 b	3547 ± 375 a	3630 ± 353 b	3543 ± 345 a
O50	4415 ± 280	0 ± 0	4471 ± 348 a	4552 ± 236 a	4456 ± 279	4171 ± 474 c	4152 ± 355 c
min dp/dt
Con-T	−3972 ± 206	0 ± 0	−2384 ± 293	−2278 ± 256	−2106 ± 122	−1703 ± 131	−1701 ± 194
O10	−4341 ± 245	0 ± 0	−3536 ± 153 b	−3175 ± 228 a	−2926 ± 141 b	−2869 ± 179 b	−2639 ± 234
O50	−4386 ± 230	0 ± 0	−3920 ± 153 c	−3848 ± 221 c	−3474 ± 195 c	−3365 ± 228 c	−3099 ± 229
CF
Con-T	12.6 ± 0.6	0 ± 0	7.3 ± 0.4	6.7 ± 0.4	6.3 ± 0.9	5.2 ± 0.5	4.5 ± 0.7
O10	13.7 ± 0.5	0 ± 0	10.5 ± 0.5 a	9.9 ± 0.6 b	9.2 ± 0.4 a	8.4 ± 0.4 b	8.3 ± 0.4 b
O50	14.2 ± 0.6	0 ± 0	11.1 ± 0.7 b	10.5 ± 0.5 b	9.9 ± 0.4 b	9.7 ± 0,5 b	9.1 ± 0.3 b

Data shown that as Mean ± SEM.

HR, heart rate; LVEDP, left ventricular end diastolic pressure; LVDP, left ventricular developed pressure and CF, coronary flow (G). Con-T, treatment control group; O10-T and O50-T mean groups that the hearts were received 10 and 50 μg/g heart oleuropein for 5 min at the early of reperfusion, respectively. I and R mean ischemic and reperfusion times, respectively. a; p < 0.05, b; p < 0.01 and c; p < 0.001 vs control group.