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. 2016 Dec 14;2016:5648390. doi: 10.1155/2016/5648390

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Copyright © 2016 Fenxia Yan et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The capability to encode spikes on barrel cortical pyramidal neurons increases after pairing WS and OS. The spikes were induced by depolarization pulse under voltage-clamp recording on glutamatergic neurons in cortical slices. (a) Traces illustrate depolarization-induced spikes on the neurons from control (blue trace) and CR-formation (dark-red). (b) shows interspike intervals for spikes 1~2 to spikes 4~5 from controls (dark-blue symbols, n = 21) and CR-formations (dark-red symbols, n = 20). (c) shows spikes per second versus normalized stimuli from control (dark-blue symbols, n = 21) and CR-formation (dark-red symbols, n = 20). (d) Traces show the measurements of spike refractory periods on the neurons from controls (dark-blue trace) and CR-formations (dark-red). (e) shows refractory periods versus spikes 1 to 4 from controls (dark-blue symbols, n = 21) and CR-formations (dark-red symbols, n = 20). (f) shows the threshold potential versus spikes 1 to 5 from controls (dark-blue symbols, n = 21) and CR-formations (dark-red symbols, n = 20).