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. 2016 Dec 14;2016:5648390. doi: 10.1155/2016/5648390

Figure 5.

Figure 5

Inhibitory synaptic transmission on barrel cortical pyramidal neurons decreases after pairing WS and OS. Spontaneous inhibitory postsynaptic currents (sIPSCs) were recorded on glutamatergic neurons in cortical slices under voltage-clamp (holding potential at −65 mV) in presence of 10 μM CNQX and 40 μM D-AP5. (a) Traces show sIPSCs recorded on the neurons from controls (dark-blue in left panel) and CR-formation (dark-red in right). The bottom traces present the expanded waveforms selected from top traces. Calibration bars are 25 pA, 1 second (top) and 100 ms (bottom). (b) shows cumulative probability versus sIPSC amplitudes from CR-formation (dark-red symbols, n = 12) and control (dark-blue symbols, n = 12). (c) shows cumulative probability versus inter-sIPSC intervals from CR-formations (dark-red symbols, n = 12) and controls (dark-blue symbols, n = 12).