Table 1.
Antigenic Group | Reference Virus | Amino Acid at Position 190 | Amino Acid at Position 212 | HI Titer of Monoclonal Antibodies | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
J14 | J9 | Q5 | U4 | U9 | U1 | U2 | MS22 | ||||
KA | C/Kanagawa/1/76 | D | E | 256,000 | <20 | 1280 | 20 | 80 | <20 | <20 | <20 |
AO | C/Aomori/74 | D | K | 1,024,000 | <20 | 640 | <20 | 40 | 3200 | 640 | <20 |
MI | C/Miyagi/77 | N | E | 1,024,000 | <20 | 6400 | 2560 | 64,000 | <20 | <20 | <20 |
Antigenic characteristics of antigenic groups of the C/Kanagawa lineage are shown by hemagglutinin inhibition (HI) titers of monoclonal antibodies.