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Forward reaction rate (v) of an enzyme-catalyzed reaction as a function of Affinity. The total concentration of substrate and product is assumed to be constant and equal to 10 mM. In solid line is represented a thermodynamic reversible reaction (vp = 100 [mmol/min mg], Kp = Ks = 1) and the dashed line represents a thermodynamically irreversible reaction (vp = 1, Kp = 10 and Ks = 1).
