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AOS pretreatment decreases DOX-induced myocardial apoptosis. (A) Representative photomicrographs at 400× magnification of mouse hearts stained with TUNEL, apoptotic cardiomyocyte nuclei appear brown-stained, whereas normal nuclei appear blue; (B) Quantitative analysis of the percentage of TUNEL-positive cells. * p < 0.05 vs. the CON group; # p < 0.05 vs. the CON + DOX group, n = 6 in each group.
