Table 1.
f free [%] | f short [%] | f long [%] | k on (s−1) | k off,1 (s−1) | k switch [10−3s−1] | k off,2 [10−3s−1] | |
---|---|---|---|---|---|---|---|
Untreated | |||||||
Heterochromatin | 6 ± 3 | 18 ± 2 | 76 ± 4 | 3.3 ± 1.7 | 1.05 ± 0.13 | 33 ± 12 | 8 ± 3 |
Euchromatin | 6 ± 3 | 31 ± 9 | 63 ± 9 | 4.0 ± 2.5 | 0.76 ± 0.21 | 16 ± 8 | 8 ± 3 |
TSA-treated | 11 ± 4 | 89 ± 4 | 2.1 ± 1.2 | 0.89 ± 0.22 | 31 ± 11 | 12 ± 4 | |
ATP-depleted | 18 ± 12 | 82 ± 12 | 1.3 ± 1.0 | 0.89 ± 0.22 | 27 ± 13 | 12 ± 2 |
(mean value ± standard deviation)
f free—free fraction, f short—shortly bound fraction, f long—long-bound fraction, k on—association rate, k off—dissociation rate, k switch—switching rate, TSA—Trichostatin A, ATP—adenosine triphosphate