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. 2016 Dec 28;16:44. doi: 10.1186/s40644-016-0102-4

Table 1.

Delphi questionnaire consensus report

Statement Respondents who agreed (%)
1 I feel that to implement an antiangiogenic therapy is important to know the infiltration of the tumour into adjacent structures such as:
i. Pleura 0.00
ii. Chest wall 0.00
iii. Bone 0.00
iv. Bronchi 83.33
v. Mediastinum 100.00
vi. Oesophagus 66.67
vii. Trachea 66.67
viii. Carina 83.33
ix. Large vessels 100.00
2 To evaluate vessels infiltration by CT scan in patients with NSCLC, I think it is sufficient to have the resolution given by a thickness of:
i. 5 mm 0.00
ii. 3 mm 83.33
iii. 1.5 mm 83.33
3 In the evaluation of treatment with antiangiogenic therapy I consider essential to know whether or not a thrombus is present 100
4 In the absence of infiltration of vessels, I think that tumour site (central or peripheral) is relevant for treatment 66.67
5 I think that cavitation is a contraindication to antiangiogenic therapy 66.67
6 I believe that the compression of a major vascular structure listed below by a secondary lymphadenopathy is a contraindication for antiangiogenic therapy
i. Vena cava 33.33
ii. Aorta 16.67
iii. Pulmonary arteries 33.33
iv. Pulmonary veins 33.33
7 I think that proximity of the disease to a large vessel is not a contraindication to antiangiogenic therapy 66.67
8 I believe that the alteration of the lung parenchyma may be a risk factor for bleeding if it is:
i. Fibrosis 0.00
ii. Bronchiectasis 50.00
iii. Emphysema 0.00
iv. Endobronchial tumour extension 83.33
v. Pleural effusion 0.00
9 In evaluating the feasibility of antiangiogenic therapy I think it is essential to know the presence of deep venous thrombosis requiring antiplatelet therapy 83.33
10 I think that pleural effusion is always a contraindication to antiangiogenic therapy 0
11 I think that pleural effusion is a contraindication to antiangiogenic therapy only if it is haemorrhagic 50
12 I think pleural effusion is a contraindication to antiangiogenic therapy only after pleurodesis. 0
13 For the chest tumour site, I consider that, to be useful to clinical practice, a structured report should include at least:
i. Cavitation 100.00
ii. Vascular infiltration 100.00
iii. Fistulas 83.33
iv. Endobronchial growth 100.00
v. Lymphangitis 66.67
vi. Margins 83.33
vii. Thromboembolism 100.00
14 For the extrathoracic tumour site, I consider that, to be useful to clinical practice, a structured report should include at least:
i. Fistulas 66.67
ii. Aneurysms 100.00
iii. Diverticula 66.67
iv. Extra-thoracic bleeding sites 100.00
v. Brain metastases 100.00
vi. Thrombi 100.00