Table 1.
Delphi questionnaire consensus report
Statement | Respondents who agreed (%) | |
---|---|---|
1 | I feel that to implement an antiangiogenic therapy is important to know the infiltration of the tumour into adjacent structures such as: | |
i. Pleura | 0.00 | |
ii. Chest wall | 0.00 | |
iii. Bone | 0.00 | |
iv. Bronchi | 83.33 | |
v. Mediastinum | 100.00 | |
vi. Oesophagus | 66.67 | |
vii. Trachea | 66.67 | |
viii. Carina | 83.33 | |
ix. Large vessels | 100.00 | |
2 | To evaluate vessels infiltration by CT scan in patients with NSCLC, I think it is sufficient to have the resolution given by a thickness of: | |
i. 5 mm | 0.00 | |
ii. 3 mm | 83.33 | |
iii. 1.5 mm | 83.33 | |
3 | In the evaluation of treatment with antiangiogenic therapy I consider essential to know whether or not a thrombus is present | 100 |
4 | In the absence of infiltration of vessels, I think that tumour site (central or peripheral) is relevant for treatment | 66.67 |
5 | I think that cavitation is a contraindication to antiangiogenic therapy | 66.67 |
6 | I believe that the compression of a major vascular structure listed below by a secondary lymphadenopathy is a contraindication for antiangiogenic therapy | |
i. Vena cava | 33.33 | |
ii. Aorta | 16.67 | |
iii. Pulmonary arteries | 33.33 | |
iv. Pulmonary veins | 33.33 | |
7 | I think that proximity of the disease to a large vessel is not a contraindication to antiangiogenic therapy | 66.67 |
8 | I believe that the alteration of the lung parenchyma may be a risk factor for bleeding if it is: | |
i. Fibrosis | 0.00 | |
ii. Bronchiectasis | 50.00 | |
iii. Emphysema | 0.00 | |
iv. Endobronchial tumour extension | 83.33 | |
v. Pleural effusion | 0.00 | |
9 | In evaluating the feasibility of antiangiogenic therapy I think it is essential to know the presence of deep venous thrombosis requiring antiplatelet therapy | 83.33 |
10 | I think that pleural effusion is always a contraindication to antiangiogenic therapy | 0 |
11 | I think that pleural effusion is a contraindication to antiangiogenic therapy only if it is haemorrhagic | 50 |
12 | I think pleural effusion is a contraindication to antiangiogenic therapy only after pleurodesis. | 0 |
13 | For the chest tumour site, I consider that, to be useful to clinical practice, a structured report should include at least: | |
i. Cavitation | 100.00 | |
ii. Vascular infiltration | 100.00 | |
iii. Fistulas | 83.33 | |
iv. Endobronchial growth | 100.00 | |
v. Lymphangitis | 66.67 | |
vi. Margins | 83.33 | |
vii. Thromboembolism | 100.00 | |
14 | For the extrathoracic tumour site, I consider that, to be useful to clinical practice, a structured report should include at least: | |
i. Fistulas | 66.67 | |
ii. Aneurysms | 100.00 | |
iii. Diverticula | 66.67 | |
iv. Extra-thoracic bleeding sites | 100.00 | |
v. Brain metastases | 100.00 | |
vi. Thrombi | 100.00 |