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. 2016 Sep 6;21(1):154–164. doi: 10.1111/jcmm.12953

Figure 6.

Figure 6

Endogenous constitutive MXRA5 has an anti‐inflammatory role in cultured proximal tubular cells. MXRA5 was knocked down and then cells were treated with 100 ng/ml TWEAK for 3 hr. TWEAK did not modify MXRA5 expression (supplemental figure). (A) MCP1 mRNA expression assessed by RT‐qPCR (N = 3, *P < 0.002 versus control). (B) MCP1 secretion assessed by ELISA in cell supernatants (N = 3, *P < 0.025). (C) Rantes mRNA expression assessed by RT‐qPCR (N = 3, *P < 0.001 versus control). (D) Cxcl16 mRNA expression assessed by RT‐qPCR (N = 3, *P < 0.001 versus control).