Figure 3.

Responses of low threshold stretch‐sensitive and high threshold afferents to a high concentration of H₂O₂ (10 mM). (A) Typical traces showing activation of low threshold stretch‐sensitive afferents (unit 1) and high threshold afferents (unit 2) by H₂O₂ (10 mM). In contrast to the high threshold afferent, the low threshold stretch‐sensitive afferent was not activated by 1 mM H₂O₂. Note that the low threshold stretch‐sensitive afferent, but not the high threshold afferent, was strongly activated by stretch with 50 mN load. (B) The shape of seven superimposed action potentials for each of the two discriminated units from tracings in A: unit 1 – low threshold stretch‐sensitive afferent; unit 2 – high threshold afferent. (C) Concentration‐response curve for activation of low threshold stretch‐sensitive afferents (n = 7, N = 6) by H₂O₂.