Skip to main content
. 2016 Dec 6;174(2):126–138. doi: 10.1111/bph.13661

Figure 5.

Figure 5

Responses of low threshold stretch‐sensitive afferents to AITC and NPPB. (A) The shape of seven superimposed action potentials for each of the three discriminated units from tracings in B: unit 1 and unit 2 – low threshold stretch‐sensitive afferents; unit 3 – high threshold afferent. (B) Typical traces showing activation of one of the low threshold stretch‐sensitive afferents (unit 2) by 100 μM but not 30 μM AITC. The high threshold afferent (unit 3) was activated by both 30 and 100 μM AITC. Note that the low threshold stretch‐sensitive afferents, but not the high threshold afferent, were strongly activated by stretch with 100 mN load. (C) and (D) – average data for concentration‐dependent activation of low threshold stretch‐sensitive afferents by AITC (n = 12, N = 8) and NPPB (n = 7, N = 7) respectively.