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. 2016 Dec 20;174(2):150–162. doi: 10.1111/bph.13665

Figure 4.

Figure 4

Effects of 10 μM chromanol 293B or 10 μM HMR1556 on dose–response relationships for phenylephrine (PE)‐induced contractions of arterial mesenteric rings with [(+) fat] (n = 5 per group) and without (−) PVAT [(−) fat] (n = 5 per group) (A,B). Dose–response relationships for PE‐induced contractions of (+) fat and (−) fat rings isolated from wild‐type (Kcnq1 +/+) [(+) fat; (−) fat, n = 7 per group] and Kcnq1 −/− mice [(+) fat; (−) fat, n = 7 per group] (C). Tension is expressed as a percentage of the steady‐state tension (100%) obtained with isotonic external 60 mM KCl. *P < 0.05, significant difference between (−) fat and (+) fat rings.