Figure 6.

Schematic representation of voltage‐dependent potassium (K_V) channels involved in vasoconstriction and ADRF‐dependent relaxation. K⁺ efflux through K_V7.1 channels does not seem to be involved in either process and the compound R‐L3 is not specific for these channels in mice. L‐type Ca_v1.2 channels play a dominant role in depolarization‐induced contraction. The focus for future studies should be other K_V channels and the use of selective pharmacological agents to identify the channels involved in this process. 4‐AP, 4‐aminopyridine.