Figure 9.

Anti‐BDNF infusion also blocks the effects of fenofibrate on the hippocampal BDNF signalling pathway. (A) Representative images of our western blotting data. (B) Quantitative analysis indicated that anti‐BDNF infusion prevented the fenofibrate‐induced enhancement of hippocampal BDNF, pERK1/2, pAkt and pCREB expression. CSDS + fenofibrate + anti‐BDNF mice displayed significantly lower BDNF, pERK1/2, pAkt and pCREB levels in the hippocampus than CSDS + fenofibrate mice. Data are expressed as means ± SEM (n = 5); * P < 0.05; n.s., no signifcance. Comparisons were made by two‐way ANOVA followed by post hoc Bonferroni's test.