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. Author manuscript; available in PMC: 2016 Dec 28.
Published in final edited form as: Q Rev Biophys. 2010 Nov 26;44(1):95–122. doi: 10.1017/S0033583510000235

Fig. 7.

Fig. 7

The substrate-bound diRNP model of box C/D MTase (same color scheme as in Fig. 6). (a) The atomic diRNP model built from the crystal structure of the halfmer RNP is consistent with the EM density of the fully assembled diRNP (Bleichert et al. 2009) (EMD-1643). Fibrillarin and the N-terminal domain of Nop56/58 could not be fitted, reflecting their observed variable positioning. Single letters refer to protein subunits. ‘N’ denotes Nop56/58, ‘F’ denotes fibrillarin and ‘L’ denotes L7Ae. (b) The substrate-bound diRNP model in surface representation. (c) Cartoon representation of the substrate-bound diRNP model.