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Correlation between potencies at inhibition of uptake and stimulation of release. hDAT (A), hSERT (B), and hNET (C). The linear regression line is shown. Values for nonparametric Spearman’s correlation (r) and significance are as follows: DAT r = 0.87, P < 0.001 (A); SERT r = 0.75, P < 0.001 (B); and NET r = 0.71, P < 0.006 (C). All of the correlations are highly significant. Amph, (+)-amphetamine.
