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. 2017 Jan;360(1):23–32. doi: 10.1124/jpet.116.236125

TABLE 2.

Seizure severity after exposure to paraoxon in VU0255035-pretreated rats compared with vehicle-pretreated rats

Data are presented as means ± S.E.M.

Time after Paraoxon Injection Behavioral Seizure Score P Value
Vehicle Group VU0255035 Group
min
5 3.33 ± 0.24 3.4 ± 0.21 0.8
10 4.33 ± 0.8 3.8 ± 0.33 0.5
15 4 ± 0.37 2.2 ± 0.26 0.003*
20 5 ± 0.51 2.4 ± 0.37 0.002*
25 5.33 ± 0.37 2.2 ± 0.33 0.0001**
30 4.67 ± 0.51 2.4 ± 0.33 0.004*
35 4.83 ± 0.58 2.8 ± 0.25 0.01***
40 4.33 ± 0.51 2.6 ± 0.21 0.008*
45 4.67 ± 0.51 3.6 ± 0.33 0.104
50 4.83 ± 0.2 4.2 ± 0.31 0.134
55 5 ± 0.24 4.4 ± 0.26 0.131
60 4.83 ± 0.32 5 ± 0.17 0.635
*

P < 0.05; **P < 0.01; ***P < 0.001.