TABLE 2.
Seizure severity after exposure to paraoxon in VU0255035-pretreated rats compared with vehicle-pretreated rats
Data are presented as means ± S.E.M.
Time after Paraoxon Injection | Behavioral Seizure Score | P Value | |
---|---|---|---|
Vehicle Group | VU0255035 Group | ||
min | |||
5 | 3.33 ± 0.24 | 3.4 ± 0.21 | 0.8 |
10 | 4.33 ± 0.8 | 3.8 ± 0.33 | 0.5 |
15 | 4 ± 0.37 | 2.2 ± 0.26 | 0.003* |
20 | 5 ± 0.51 | 2.4 ± 0.37 | 0.002* |
25 | 5.33 ± 0.37 | 2.2 ± 0.33 | 0.0001** |
30 | 4.67 ± 0.51 | 2.4 ± 0.33 | 0.004* |
35 | 4.83 ± 0.58 | 2.8 ± 0.25 | 0.01*** |
40 | 4.33 ± 0.51 | 2.6 ± 0.21 | 0.008* |
45 | 4.67 ± 0.51 | 3.6 ± 0.33 | 0.104 |
50 | 4.83 ± 0.2 | 4.2 ± 0.31 | 0.134 |
55 | 5 ± 0.24 | 4.4 ± 0.26 | 0.131 |
60 | 4.83 ± 0.32 | 5 ± 0.17 | 0.635 |
P < 0.05; **P < 0.01; ***P < 0.001.