Table 1.
Patient Baseline Characteristics.
Patient Characteristic (n=175 patients; 176 diagnoses) | Number of patients (%) |
---|---|
| |
Age at diagnosis (mean, range) | 63 years, 27–87 years |
| |
Gender | |
Male | 86 (49.1%) |
Female | 89 (50.9%) |
| |
Ashkenazi Jewish (AJ) ancestry | 98 (56.0%) |
| |
Pathology | |
Adenocarcinoma NOS | 171 (97.7%) |
Acinar | 2 (1.1%) |
Mixed (neuroendocrine, acinar, and ductal/adenocarcinoma features) | 3 (1.7%) |
| |
Personal Cancer History | |
>1 Primary cancer | 46 (26.3%) |
Breast | 16 (9.1%) |
Prostate | 14 (8.0%) |
Melanoma | 9 (5.1%) |
Urinary tract (bladder, renal) | 4 (2.3%) |
Metachronous pancreas cancer | 1 (0.6%) |
Other | 10 (5.7%) |
| |
Family History | |
FDR and/or SDR with breast cancer: | |
0 | 89 (50.9%) |
1 | 57 (32.6) |
2 | 22 (12.6%) |
≥3 | 7 (4.0%) |
FDR and/or SDR with ovarian cancer: | |
0 | 150 (85.7%) |
1 | 24 (13.7%) |
2 | 1 (0.6%) |
≥3 | 0 (0.0%) |
FDR and/or SDR with colorectal cancer: | |
0 | 127 (72.6%) |
1 | 38 (21.7%) |
2 | 3 (1.7%) |
≥3 | 7 (4.0%) |
FDR and/or SDR with pancreatic cancer: | |
0 | 114 (65.1%) |
1 | 50 (28.6%) |
2 | 11 (6.3%) |
≥3 | 0 (0.0%) |
Familial Pancreatic cancer (PC in ≥2 FDRs including proband): | 40 (22.9%) |
FDR = first degree relative; SDR = second degree relative; PC = pancreatic cancer