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. Author manuscript; available in PMC: 2016 Dec 28.
Published in final edited form as: Cancer. 2015 Oct 6;121(24):4382–4388. doi: 10.1002/cncr.29664

Table 2.

Evaluation and Identification of Cancer Predisposition Syndromes in Pancreatic Cancer Patients.

Syndrome # of patients who completed evaluation Mutation prevalence
Overall 159 24 (15.1%)
HBOC
(BRCA1, BRCA2)
151 17 (11.3%)
4 BRCA1 mutations;
13 BRCA2 mutations
Lynch syndrome
(MLH1, MSH2, MSH6, PMS2)
36 4 (11.1%)
1 MLH1 mutation;
2 MSH2 mutations;
1 MSH6 mutation
PALB2 48 1 (2.1%)
FAMMM (p16) 17 2 (11.8%)

HBOC = Hereditary Breast and Ovarian Cancer syndrome;

FAMMM = Familial Atypical Multiple Mole Melanoma syndrome

HHS Vulnerability Disclosure