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. Author manuscript; available in PMC: 2016 Dec 28.
Published in final edited form as: Cancer. 2015 Oct 6;121(24):4382–4388. doi: 10.1002/cncr.29664

Table 3.

Germline Mutation Prevalence in Pancreatic Cancer Patient Cohorts.

Patient population N Number of patients tested Pathogenic mutation identified BRCA1 mutation BRCA2 mutation Other Gene
Ashkenazi Jewish 98 96 15 (15.6%) 2 11 2
Non-Ashkenazi Jewish 77 63 9 (14.3%) 2 2 5
Early-onset (age ≤50) 26 21 6 (28.6%) 2 0 4
Late-onset (age ≥70) 51 46 3 (6.5%) 2 1 0
Familial Pancreatic 40 34 2 (5.9%) 1 1 0
HHS Vulnerability Disclosure