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2-Kase inhibition by Citrate. (A) Double reciprocal plot with F6P as the variable substrate showing competitive inhibition, where v=Vmax[S]/{Km(1+[I]/Kis)+[S]} (B) Double reciprocal plot with ATP as the variable substrate showing non-competitive inhibition, where v=Vmax[S]/{Km(1+[I]/Kis)+[S](1+[I]/Kii)}.
