Table 1. Characteristics of the analyzed sample.
| HSS | LSS | Control Group | ||
|---|---|---|---|---|
| n = 11 | n = 9 | n = 25 | ||
| age (years) | mean (SD) | 23.4 (3.8) | 23.9 (4.0) | 28.3 (5.5) |
| range | (19–30) | (18–32) | (20.6–46.6) | |
| duration of illness (years) | mean (SD) | 5.1 (5.7) | 3.7 (3.2) | — |
| range | (1–17) | (1–10) | ||
| subtype AN-R | n (%) | 10 (90.9) | 7 (77.8) | — |
| BMI: first measurement (kg/m2) | mean (SD) | 13.6 (1.3) | 16.2 (0.9) | 21.2 (1.8) |
| range | (11.8–15.7) | (14.4–17.5) | (18.0–25.0) | |
| BMI: last measurement (kg/m2) | mean (SD) | 17.0 (1.7) | 17.1 (0.7) | — |
| range | (14.5–19.0) | (16.0–18.4) | ||
| leptin: first measurement (μg/l) | mean (SD) | 0.69 (0.8) | 2.02 (3.0) | 8.9 (5.5) |
| range | (0.1–3.0) | (0.1–9.7) | (1.6–22.2) | |
| leptin: last measurement (μg/l) | mean (SD) | 5.4 (5.9) | 3.1 (1.5) | — |
| range | (0.8–15.4) | (0.8–5.9) | ||
| duration of inpatient treatment (days) | mean (SD) | 128.9 (63.9) | 68.2 (14.8) | — |
| range | (52–231) | (42–84) | ||
| duration of participation (days) | mean (SD) | 114.8 (59.8) | 64.8 (12.7) | — |
| range | (39–223) | (39–83) | ||
| number of serum measurements | mean (SD) | 15.7 (8.4) | 9.8 (1.9) | — |
| range | (5–31) | (6–12) | ||
| Mental health comorbiditiesa (at enrolment) | n(%) | |||
| major depression (current) | 4 (36.4) | 6 (66.7) | 0 | |
| minor depression (current) | 1 (9.1) | 1 (11.1) | 0 | |
| panic disorder (current) | 1 (9.1) | 3 (33.3) | 0 | |
| generalized anxiety (current) | 1 (9.1) | 0 | 0 | |
| social phobia (current) | 2 (18.2) | 0 | 0 | |
| Obsessive compulsive (current) | 0 | 1 (11.1) | 0 |
HSS = patient group with high symptom severity; LSS = patient group with less severe symptoms; AN-R: restrictive subtype; SD = standard deviation
a diagnoses based on the Structured Clinical Interview for DSM-IV
Note: Out of N = 28 AN patients enrolled in the study, only N = 20 could finally be included in the data analysis (for reasons described in the text). Only the participants finally analyzed are described in this table.