Table 1.
Estimated rate of total lipase activity in testis co-culture: Comparison with rates reported in testis tissue in the literature
| Reaction | Mean (SD) reaction rate (picomoles/mg protein/minute) |
| DEHP -> MEHP | 0.5 (0.3) |
| DBP -> MBP | 57 (20) |
| DEP -> MEP | 242 (113) |
| Range of calculated metabolic rate for phthalates in the testis co-culture: 0.5–242 picomoles/mg protein/min. | |
| Reaction | Reported reaction rate (picomoles/mg protein/minute) |
| Conversion DEHP->MEHP (Human testes, subcellular fractions)a |
~3 |
| Lipoprotein lipase activity (Rat testes, whole tissue)b | 18 |
| Triglyceride lipase activity (rat germ cells)c | 283 |
| Reported rates for lipases and phthalate metabolism in rat and human testes in literature: ~3–283 picomoles/mg protein/min. | |