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. 2016 Dec 28;11(12):e0168718. doi: 10.1371/journal.pone.0168718

Table 4. ORs (95% CIs) for hearing lossa by joint effect between earphone use time and blood lead level (n = 1,036).

Variables Low lead High lead Lead within strata of using time
Low using time Ref. 1.14 (0.42, 3.13) 1.14 (0.42, 3.13)
High using time 1.79 (0.66, 4.85) 3.23 (1.44, 7.27) 1.93 (0.75, 4.96)
Using time within strata of lead 1.79 (0.66, 4.85) 2.48 (0.97, 6.38)

aHearing loss was defined as pure-tone average ≥ 25 dB.

Measure of interaction on additive scale: RERI (95% CI) = 1.30 (−0.83 to 3.43); p = 0.232.

Measure of interaction on multiplicative scale: ratio of ORs (95% CI) = 1.58 (0.42 to 5.97); p = 0.499.

Models were adjusted for age, sex, monthly income, education levels, smoking status, BMI, occupational noise, loud noise, firearm noise, hypertension, and diabetes. Earphone use time models were further adjusted for lead, and blood lead models were further adjusted for earphone use time.