Figure 1.

GLP-1 does not affect the migration and accumulation of infused MSCs into the pancreatic tissues of NOD mice. Diabetic NOD mice were infused with MSCs and treated intraperitoneally with GLP-1 or vehicle daily for 42 d. The indicated tissues were dissected from some mice of each group and the content of Alu element DNA was determined by quantitative RT-PCR. Data are expressed as the mean ± SEM of each group of mice (n = 6 per group per time point from three separate experiments. *P < 0.05 versus mice at 14 d post treatment. †P < 0.05 versus mice at 42 d post treatment.