Figure 5.

Treatment with MSCs and GLP-1 alters plasma cytokine levels in NOD mice. Following treatment with MSCs and GLP-1, plasma IFN-γ, TNF-α, IL-10 and TGF-β1 levels in individual mice were measured. Data are expressed as the mean ± SEM of individual group of mice (n = 6 per group per time point) from three separate experiments. (A) Plasma IFN-γ levels. (B) Plasma TNF-α levels. (C) Plasma IL-10 levels. (D) Plasma TGF-β1 levels. *P < 0.05 versus diabetic controls. †P < 0.05 versus mice treated with MSCs alone.