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. Author manuscript; available in PMC: 2017 Mar 31.
Published in final edited form as: Expert Rev Precis Med Drug Dev. 2016 Mar 31;1(2):207–226. doi: 10.1080/23808993.2016.1164013

Figure 5.

Figure 5

(a) Illustration of the neighborhood around the pixel of interest based on the user defined neighborhood parameter, d (b) Example 5×5 input matrix with values ranging from 1 to 5. (c) Neighborhood gray tone difference matrix for d=1.