Table 3. Differences in Echocardiographic Parameters between Patients with Aldosterone-producing Adenoma and Bilateral Adrenal Hyperplasia.
Parameter | APA (n=8) | BAH (n=15) | P value |
---|---|---|---|
Parameters for structural abnormality | |||
LVEF, % | 68.5 (61.0–76.0) | 71.0 (61.0–76.0) | 0.112 |
LVEDD, mm | 48.0 (44.0–53.0) | 50.0 (43.0–57.0) | 0.516 |
LVESD, mm | 30.5 (27.0–36.0) | 30.0 (26.0–36.0) | 0.795 |
IVSd, mm | 12.0 (8.0–13.0) | 11.0 (8.0–20.0) | 0.265 |
PWd, mm | 11.0 (7.0–14.0) | 11.0 (7.0–16.0) | 0.578 |
LV mass, g | 234.6 (187.5–259.6) | 174.5 (133.6–294.4) | 0.034 |
LVMI, g/m2 | 127.3 (101.9–153.6) | 99.8 (74.7–136.2) | 0.043 |
LAVI, mL/m2 | 38.7 (20.6–54.0) | 30.2 (22.1–50.4) | 0.029 |
RWT | 0.45 (0.32–0.58) | 0.44 (0.27–0.70) | 0.561 |
Parameters for diastolic function | |||
E velocity, m/sec | 0.8 (0.5–1.0) | 0.7 (0.4–1.0) | 0.260 |
A velocity, m/sec | 0.69 (0.72–1.11) | 0.65 (0.47–0.84) | 0.047 |
E/A ratio | 1.0 (0.7–1.4) | 1.2 (0.5–2.0) | 0.458 |
Deceleration time, msec | 181.0 (141.0–237.0) | 194.0 (151.0–260.0) | 0.183 |
E’, m/sec | 0.07 (0.04–0.11) | 0.06 (0.03–0.11) | 0.945 |
E/E’ ratio | 12.3 (6.8–20.0) | 10.5 (6.0–20.0) | 0.516 |
Values are expressed as median (range). The Mann-Whitney U test was used to compare differences in continuous variables between APA and BAH. APA, aldosterone-producing adenoma; BAH, bilateral adrenal hyperplasia; LVEF, left ventricular ejection fraction; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; IVSd, interventricular septum diameter; PWd, posterior wall diameter; LV, left ventricular; LVMI, left ventricular mass index; LAVI, left atrial volume index; RWT, relative wall thickness.