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. 2016 Nov 3;31(4):567–576. doi: 10.3803/EnM.2016.31.4.567

Table 4. Associations between Inflammatory Markers Associated with Oxidative Stress and Echocardiographic Parameters.

Parameter Correlation coefficient
IL-1β IL-6 IL-8 MCP-1 TNF-α MMP-2 MMP-9
Structural abnormality
 LVEF, % –0.162 0.023 –0.021 0.442 0.309 0.200 0.459
 LVEDD, mm 0.343 0.032 0.177 0.290 0.035 0.095 –0.313
 LVESD, mm 0.411 0.106 0.196 –0.083 –0.192 –0.099 –0.622a
 IVSd, mm 0.424 0.276 –0.060 –0.206 –0.008 –0.086 0.538a
 PWd, mm 0.099 –0.054 –0.315 –0.242 –0.205 –0.145 –0.061
 LV mass, g 0.386 0.478 –0.040 0.186 0.246 0.206 0.553a
 LVMI, g/m2 0.487 0.444 –0.101 –0.043 0.032 –0.037 0.329
 LAVI, mL/m2 0.694a 0.060 –0.001 –0.165 0.077 –0.115 0.040
 RWT –0.402 0.127 0.218 0.164 0.223 0.114 0.182
Function
 E velocity, m/sec 0.587 0.680a 0.071 –0.214 –0.086 –0.160 0.265
 A velocity, m/sec –0.172 0.401 0.425 0.615a 0.819a 0.751a 0.502
 E/A ratio 0.52 0.402 0.029 –0.472 –0.436 –0.472 –0.133
 Deceleration time, msec 0.002 –0.100 0.053 0.446 0.120 0.267 –0.131
 E’, m/sec 0.335 0.127 –0.354 –0.517a –0.422 –0.371 –0.046
 E/E’ ratio 0.300 0.418 0.512 0.179 0.297 0.505 –0.031

Spearman partial correlation adjusted for age and sex was used to examine the relationships between inflammatory markers associated with oxidative stress and echocardiographic parameters.

IL, interleukin; MCP, monocyte chemoattractant protein; TNF-α, tumor necrosis factor α; MMP, matrix metalloproteinase; LVEF, left ventricular ejection fraction; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; IVSd, interventricular septum diameter; PWd, posterior wall diameter; LV, left ventricular; LVMI, left ventricular mass index; LAVI, left atrial volume index; RWT, relative wall thickness.

aP<0.05, after adjustment for age and sex.