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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: J Clin Lipidol. 2016 Mar 8;10(4):808–815. doi: 10.1016/j.jacl.2016.03.001

Table 2.

ApoA-II proteoforms detected by MSIA

Label Proteoform Theoretical
m/z value
M Monomer apoA-II– cysteinylation on C in position 6 & cyclization on N-terminal Q residue 8807.9
Mox Monomer apoA-II– cysteinylation on C in position 6 & cyclization on N-terminal Q residue oxidized 8823.9
MQ Monomer apoA-II– cysteinylation on C in position 6 & cyclization on N-terminal Q residue missing C-terminal Q residue 8679.8
MQox Monomer apoA-II– cysteinylation on C in position 6 & cyclization on N-terminal Q residue missing C-terminal Q residue oxidized 8695.8
MTQ Monomer apoA-II– cysteinylation on C in position 6 & cyclization on N-terminal Q residue missing C-terminal TQ dipeptide 8578.7
MTQox Monomer apoA-II– cysteinylation on C in position 6 & cyclization on N-terminal Q residue missing C-terminal TQ dipeptide oxidized 8594.7
D Dimer apoA-II– 2 × monomer (through S-S bond) + 2 × cyclization on N-terminal Q residues 17377.7
Dox Dimer apoA-II– 2 × monomer (through S-S bond) + 2 × cyclization on N-terminal Q residues oxidized 17393.7
DQ Dimer apoA-II– lacking 1 × C-terminal Q residue (on one monomer) 17249.5
DQox Dimer apoA-II– lacking 1 × C-terminal Q residue oxidized 17265.6
D2Q Dimer apoA-II– lacking 2 × C-terminal Q residues (on both monomers) 17121.4
D2Qox Dimer apoA-II– lacking 2 × C-terminal Q residues oxidized 17137.5

MSIA: Mass Spectrometric Immunoassay.