. Author manuscript; available in PMC: 2017 Jul 1.

Published in final edited form as: J Clin Lipidol. 2016 Mar 8;10(4):808–815. doi: 10.1016/j.jacl.2016.03.001

Table 6.

Distribution of oxidized apoA-II proteoforms in diabetic and non-diabetic samples

Proteoform	No-Diabetes with 100% oxidized	Diabetes With 100% oxidized	p-value
Monomer (M)	0%	16.6%	0.04
Monomer missing C - terminal glutamine (MQ)	72%	66.6%	0.67
Monomer missing C-terminal tryptophan and glutamine (MTQ)	0%	0%	-
Dimer (D)	4%	17%	0.12
Dimer missing C-terminal glutamine (DQ)	8%	20%	0.21
Dimer missing two C-terminal glutamines (D2Q)	0%	36%	0.022

In some samples, only the oxidized version of the proteoform was detected without any detectable levels of the native form. In these cases, 100% of the available proteoform was oxidized (100% oxidized). This occurred more often in samples from patients with diabetes.