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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Stem Cells. 2016 Nov 10;35(1):35–41. doi: 10.1002/stem.2507

Table 4. Differing characteristics between the naïve and primed states from combined literature.

Naïve Primed
Morphology mounded flat
Single-cell passage (w/o ROCKi) yes no
Relative gene expression:
 TBX3 high low
 DNMT3L high low
 IL6ST (GP130) high low
 DNMT3B low high
 CD24 low high
 Transposable elements high low
 HERVK high low
OCT4 enhancer use distal proximal
Relative H3K27me3 marks low high
X-activation XaXa XaXi
Metabolism Ox-Phos Glycolytic